BDBM50007567 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL64875::OCTOCLOTHEPIN-R
SMILES CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12
InChI Key InChIKey=XRYLGRGAWQSVQW-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50007567
Affinity DataKi: 3.60nMAssay Description:In vitro binding affinity towards Dopamine receptor D2 in rat tissue homogenate using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Half-maximal inhibition of [3H]spiperone binding to Dopamine receptor D2 in rat striatal homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]spiperone (0.5 nM) from rat corpus striatum dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Displacement of [3H]prozosin from human cloned dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiroperidolMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Ability to inhibit binding of [3H]-SPI to dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair